Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.55 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30786697 | 1.00 | DPP4 (0.55) | DPP4DPP8KCNH2DPP7 | |
| SCHEMBL8255180 | 0.95 | DPP4 (0.63) | DPP4DPP8KCNH2DPP7 | |
| SCHEMBL2860054 | 0.85 | DPP4 (0.55) | DPP4DPP8DPP7 | |
| SCHEMBL2860736 | 0.85 | DPP4 (0.55) | DPP4DPP8DPP7 | |
| SCHEMBL3776140 | 0.84 | DPP4 (0.47) | DPP4DPP8KCNH2 | |
| SCHEMBL3776139 | 0.84 | DPP4 (0.47) | DPP4DPP8KCNH2 | |
| SCHEMBL3764856 | 0.81 | DPP4 (0.48) | DPP4DPP8 | |
| SCHEMBL12189888 | 0.80 | DPP4 (0.60) | DPP4DPP8KCNH2DPP7 | |
| SCHEMBL1509230 | 0.80 | DPP4 (0.49) | DPP4DPP8DPP7 | |
| SCHEMBL29196906 | 0.80 | DPP4 (0.55) | DPP4DPP8KCNH2DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720540-A | Sitagliptin intermediate and preparation method of sitagliptin | 宜昌东阳光制药有限公司 | 2024-03-19 | — | — | CN | disclosed |