Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.63 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.63 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30786697 | 0.95 | DPP4 (0.55) | DPP4DPP8DPP7KCNH2 | |
| SCHEMBL29196909 | 0.95 | DPP4 (0.55) | DPP4DPP8DPP7KCNH2 | |
| SCHEMBL5041276 | 0.82 | DPP4 (0.66) | DPP4DPP8DPP7KCNH2 | |
| SCHEMBL3776139 | 0.82 | DPP4 (0.47) | DPP4DPP8KCNH2 | |
| SCHEMBL3776140 | 0.82 | DPP4 (0.47) | DPP4DPP8KCNH2 | |
| SCHEMBL2860736 | 0.81 | DPP4 (0.55) | DPP4DPP8DPP7 | |
| SCHEMBL2860054 | 0.81 | DPP4 (0.55) | DPP4DPP8DPP7 | |
| SCHEMBL8245497 | 0.80 | DPP4 (0.68) | DPP4DPP8DPP7KCNH2 | |
| SCHEMBL13852630 | 0.80 | DPP4 (0.68) | DPP4DPP8DPP7KCNH2 | |
| SCHEMBL8245496 | 0.80 | DPP4 (0.68) | DPP4DPP8DPP7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006104997-A2 | TARTARIC ACID SALTS OF A DIPEPTIDYL PEPTIDASE-IV INHIBITOR | MERCK & CO., INC. (US) | 2006-10-05 | — | — | WO | disclosed |