Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 2/20 | 0.34 |
| ▸ | GALR2 | O43603 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29197525 | 0.73 | GAA (0.45) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL30888289 | 0.73 | GAA (0.45) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL27647530 | 0.66 | NSD2 (0.44) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL10348239 | 0.65 | GAA (0.42) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL19911459 | 0.64 | MGAM (0.39) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL3285085 | 0.62 | MAPT (0.42) | GAAALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL3104435 | 0.61 | RAB9A (0.66) | GAAALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL17783681 | 0.60 | GAA (0.45) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL8053279 | 0.59 | TSHR (0.58) | GAAALDH1A1SMN1; SMN2HPGDPKM | |
| SCHEMBL22120407 | 0.58 | KMT2A (0.53) | GAAALDH1A1SMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117940437-A | DNA-PK selective inhibitor and preparation method and application thereof | 首药控股(北京)股份有限公司 | 2024-04-26 | — | — | CN | disclosed |