Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 18/20 | 0.52 |
| ▸ | CRBN | Q96SW2 | 18/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23301516 | 0.89 | DDB1 (0.62) | DDB1CRBN | |
| SCHEMBL24125822 | 0.89 | DDB1 (0.62) | DDB1CRBN | |
| SCHEMBL24125697 | 0.89 | DDB1 (0.62) | DDB1CRBN | |
| SCHEMBL31232850 | 0.86 | CRBN (0.63) | DDB1CRBNPDE4B | |
| SCHEMBL29347259 | 0.85 | DDB1 (0.58) | DDB1CRBNPDE4B | |
| SCHEMBL31306721 | 0.84 | DDB1 (0.49) | DDB1CRBN | |
| SCHEMBL20595415 | 0.81 | DDB1 (0.74) | DDB1CRBN | |
| SCHEMBL21903077 | 0.81 | DDB1 (0.74) | DDB1CRBN | |
| SCHEMBL29744797 | 0.81 | DDB1 (0.74) | DDB1CRBN | |
| SCHEMBL31306834 | 0.81 | DDB1 (0.55) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367113-A1 | COMPOUNDS FOR TARGETING DEGRADATION OF IRAK4 PROTEINS | Biogen MA Inc. (US) | 2024-05-15 | — | — | EP | disclosed |
| CN-117940414-A | Compounds for targeting IRAK4 protein degradation | 渤健马萨诸塞州股份有限公司 | 2024-04-26 | — | — | CN | disclosed |
| WO-2023283610-A1 | COMPOUNDS FOR TARGETING DEGRADATION OF IRAK4 PROTEINS | BIOGEN MA INC. (US) | 2023-01-12 | — | — | WO | disclosed |