Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 15/20 | 0.63 |
| ▸ | DDB1 | Q16531 | 14/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30830879 | 0.91 | CRBN (0.68) | CRBNDDB1POLB | |
| SCHEMBL23301622 | 0.88 | CRBN (0.67) | CRBNDDB1POLB | |
| SCHEMBL25187964 | 0.88 | CRBN (0.67) | CRBNDDB1POLB | |
| SCHEMBL24206650 | 0.88 | CRBN (0.67) | CRBNDDB1POLB | |
| SCHEMBL29197848 | 0.86 | DDB1 (0.52) | CRBNDDB1PDE4B | |
| SCHEMBL29223642 | 0.85 | CRBN (0.63) | CRBNDDB1POLB | |
| SCHEMBL30643683 | 0.85 | DDB1 (0.55) | CRBNDDB1 | |
| SCHEMBL30706186 | 0.84 | DDB1 (0.55) | CRBNDDB1 | |
| SCHEMBL30706246 | 0.84 | DDB1 (0.55) | CRBNDDB1 | |
| SCHEMBL30643603 | 0.83 | CRBN (0.61) | CRBNDDB1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709730-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | Celgene Corporation (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233742-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | CELGENE CORPORATION (US) | 2024-11-14 | — | — | WO | disclosed |