Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACR | P10323 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 7/20 | 0.55 |
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1686391 | 0.88 | TP53 (0.62) | ACRTP53SMN1; SMN2MAPTNPC1 | |
| SCHEMBL27237216 | 0.88 | ACR (0.58) | ACRTP53SMN1; SMN2MAPTHPGD | |
| SCHEMBL1686347 | 0.88 | POLB (0.66) | ACRTP53SMN1; SMN2MAPTHPGD | |
| SCHEMBL1686476 | 0.88 | MAPT (0.72) | ACRTP53SMN1; SMN2MAPTNPC1 | |
| SCHEMBL768649 | 0.88 | ACR (0.63) | ACRTP53SMN1; SMN2MAPTNPC1 | |
| SCHEMBL15468398 | 0.87 | MAPT (0.68) | ACRTP53SMN1; SMN2MAPTNPC1 | |
| SCHEMBL13361728 | 0.87 | ACR (0.57) | ACRTP53MAPTHPGDALDH1A1 | |
| SCHEMBL21523600 | 0.87 | ACR (0.56) | ACRTP53MAPTHPGDALDH1A1 | |
| SCHEMBL1686535 | 0.86 | ACR (0.56) | ACRTP53MAPTHPGDALDH1A1 | |
| SCHEMBL766707 | 0.85 | ACR (0.55) | ACRTP53MAPTHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117417334-A | Azole derivative containing isoxazole structure, and preparation method and application thereof | 沈阳药科大学 | 2024-01-19 | — | — | CN | disclosed |