Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2568738 | 0.98 | L3MBTL1 (0.49) | L3MBTL1TDP1ALDH1A1TSHRKDM4E | |
| SCHEMBL24773083 | 0.97 | TSHR (0.44) | L3MBTL1TDP1ALDH1A1TSHRKDM4E | |
| SCHEMBL27032384 | 0.97 | TSHR (0.44) | L3MBTL1TDP1ALDH1A1TSHRKDM4E | |
| SCHEMBL24675883 | 0.95 | L3MBTL1 (0.49) | L3MBTL1TDP1ALDH1A1TSHRKDM4E | |
| SCHEMBL20133100 | 0.95 | L3MBTL1 (0.49) | L3MBTL1TDP1ALDH1A1TSHRKDM4E | |
| SCHEMBL12013298 | 0.95 | TSHR (0.48) | L3MBTL1TDP1ALDH1A1TSHRKDM4E | |
| SCHEMBL10316643 | 0.95 | TSHR (0.48) | L3MBTL1TDP1ALDH1A1TSHRKDM4E | |
| SCHEMBL6379981 | 0.95 | TSHR (0.48) | L3MBTL1TDP1ALDH1A1TSHRKDM4E | |
| SCHEMBL30388469 | 0.95 | TSHR (0.48) | L3MBTL1TDP1ALDH1A1TSHRKDM4E | |
| SCHEMBL25622617 | 0.95 | TSHR (0.48) | L3MBTL1TDP1ALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117425661-A | Macrocyclic LRRK2 kinase inhibitors | 法国施维雅药厂 | 2024-01-19 | — | — | CN | disclosed |