Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 18/20 | 0.40 |
| ▸ | HTR2B | P41595 | 18/20 | 0.40 |
| ▸ | HTR2A | P28223 | 12/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14163377 | 0.78 | PARP1 (0.38) | PARP1HTR2CHTR2BHTR2ATP53 | |
| SCHEMBL30169487 | 0.75 | HTR2C (0.70) | PARP1HTR2CHTR2BHTR2A | |
| SCHEMBL13950159 | 0.74 | HTR2C (0.39) | PARP1HTR2CHTR2BHTR2A | |
| SCHEMBL5900855 | 0.74 | HTR2C (0.39) | PARP1HTR2CHTR2BHTR2A | |
| SCHEMBL17672393 | 0.73 | HTR6 (0.39) | PARP1HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL31437688 | 0.73 | HTR2C (0.38) | HTR2CHTR2BHTR2A | |
| SCHEMBL22044699 | 0.73 | HTR6 (0.39) | PARP1HTR2CHTR2BHTR2A | |
| SCHEMBL22025278 | 0.73 | HTR6 (0.39) | PARP1HTR2CHTR2BHTR2A | |
| SCHEMBL9243589 | 0.72 | GRM5 (0.40) | — | |
| Trifluoroacetic Acid SCHEMBL31257489 | 0.72 | PARP1 (0.39) | PARP1HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117903122-A | Preparation method of cefbuperazine Luo Zhina dicyclo ester side chain | 杭州善礼生物医药科技有限公司 | 2024-04-19 | — | — | CN | disclosed |