Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 known ✓ | P41145 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GLB1 | P16278 | 1/20 | 0.32 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28296552 | 0.94 | CA2 (0.38) | CA2MAPK1GLB1OGAUSP2 | |
| Acetic Acid SCHEMBL28603498 | 0.91 | CA2 (0.32) | CA2MAPK1GLB1OGA | |
| Acetic Acid SCHEMBL28640717 | 0.87 | GUSB (0.39) | — | |
| Water SCHEMBL28177908 | 0.86 | GLB1 (0.33) | GLB1 | |
| Bromide SCHEMBL5168952 | 0.86 | GLB1 (0.33) | GLB1 | |
| Acetic Acid SCHEMBL27808876 | 0.86 | FFAR3 (0.35) | — | |
| Acetic Acid SCHEMBL28308309 | 0.85 | CA2 (0.34) | CA2MAPK1GLB1OGAUSP2 | |
| Acetic Acid SCHEMBL3459442 | 0.85 | CA2 (0.34) | CA2MAPK1GLB1OGAUSP2 | |
| Hydrochloric Acid SCHEMBL29290772 | 0.84 | GLB1 (0.32) | GLB1 | |
| SCHEMBL28796592 | 0.84 | GLB1 (0.35) | CA2GLB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112067674-B | Molecularly imprinted electrochemical sensor and folic acid content detection method thereof | 常州市新鸿医药化工技术有限公司 | 2024-12-20 | — | — | CN | claimed |
| CN-118956507-A | Composition with oil and rust removing functions and application thereof | 北京蓝星清洗有限公司 | 2024-11-15 | — | — | CN | claimed |
| CN-114672078-B | Modified rubber and preparation method thereof | 广东越境智能科技有限公司 | 2024-03-05 | — | — | CN | claimed |
| CN-114672078-A | Modified rubber and preparation method thereof | 施以进 | 2022-06-28 | — | — | CN | claimed |
| CN-112067674-B | Molecularly imprinted electrochemical sensor and folic acid content detection method thereof | 常州市新鸿医药化工技术有限公司 | 2024-12-20 | — | — | CN | disclosed |
| CN-118956507-A | Composition with oil and rust removing functions and application thereof | 北京蓝星清洗有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-114672078-B | Modified rubber and preparation method thereof | 广东越境智能科技有限公司 | 2024-03-05 | — | — | CN | disclosed |
| CN-114672078-A | Modified rubber and preparation method thereof | 施以进 | 2022-06-28 | — | — | CN | disclosed |