Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20621305 | 0.83 | TSHR (0.44) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL16719563 | 0.81 | KDM4E (0.39) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL2059537 | 0.81 | KDM4E (0.71) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL1245242 | 0.81 | TSHR (0.42) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| Acetic Acid SCHEMBL28743789 | 0.81 | SMN1; SMN2 (0.46) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL19779772 | 0.79 | SSTR4 (0.44) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL28644588 | 0.77 | ALDH1A1 (0.40) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL27548181 | 0.77 | TSHR (0.50) | KDM4EALDH1A1TSHRGAASSTR4 | |
| SCHEMBL19880467 | 0.77 | TSHR (0.44) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL16719452 | 0.76 | NPC1 (0.43) | KDM4EHSD17B10ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946058-A | Preparation method of 3-isochromone | 上海试四化学品有限公司 | 2024-04-30 | — | — | CN | disclosed |