Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ESRRB | O95718 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESRRA | P11474 | 1/20 | 0.44 |
| ▸ | ESRRG | P62508 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL426841 | 0.96 | MAPT (0.64) | MAPTLMNAALDH1A1GPR119NAMPT | |
| SCHEMBL5573222 | 0.86 | MAPT (0.76) | MAPTLMNAALDH1A1GPR119NAMPT | |
| SCHEMBL1129430 | 0.85 | MAPT (0.55) | MAPTLMNAALDH1A1GPR119NAMPT | |
| SCHEMBL29199351 | 0.85 | MAPT (0.57) | MAPTLMNAALDH1A1GPR119NAMPT | |
| SCHEMBL29089126 | 0.84 | KMT2A (0.61) | MAPTLMNAALDH1A1GPR119SMN1; SMN2 | |
| SCHEMBL12089783 | 0.81 | MAPT (0.65) | MAPTLMNAALDH1A1GPR119NAMPT | |
| SCHEMBL1217336 | 0.81 | MAPT (0.69) | MAPTLMNAALDH1A1GPR119NAMPT | |
| SCHEMBL29434979 | 0.81 | GPR119 (0.57) | MAPTLMNAALDH1A1GPR119NAMPT | |
| SCHEMBL2567243 | 0.81 | GPR119 (0.57) | MAPTLMNAALDH1A1GPR119NAMPT | |
| SCHEMBL2056118 | 0.80 | GPR119 (0.77) | MAPTLMNAALDH1A1GPR119NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160311-B | Difunctional compound for EGFR degradation and application thereof | 北京康辰药业股份有限公司 | 2024-03-15 | — | — | CN | disclosed |