Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | JMJD6 | Q6NYC1 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28337899 | 0.87 | BRD4 (0.49) | BRD4MAPTLMNANPC1RAB9A | |
| SCHEMBL25347956 | 0.85 | BRD4 (0.48) | BRD4MAPTLMNANPC1RAB9A | |
| SCHEMBL28340169 | 0.84 | BRD4 (0.47) | BRD4MAPTLMNANPC1RAB9A | |
| SCHEMBL22395439 | 0.84 | BRD4 (0.47) | BRD4MAPTLMNANPC1RAB9A | |
| SCHEMBL25227115 | 0.81 | MAPT (0.51) | BRD4MAPTLMNANPC1RAB9A | |
| SCHEMBL30697148 | 0.81 | BRD4 (0.45) | BRD4MAPTLMNANPC1RAB9A | |
| SCHEMBL29272499 | 0.80 | KDM4E (0.44) | BRD4MAPTLMNANPC1RAB9A | |
| SCHEMBL16505732 | 0.80 | BRD4 (0.60) | BRD4MAPTLMNACYP1A2NPSR1 | |
| SCHEMBL31453471 | 0.80 | BRD4 (0.60) | BRD4MAPTLMNACYP1A2NPSR1 | |
| SCHEMBL21843252 | 0.78 | BRD4 (0.56) | BRD4MAPTNPC1CYP1A2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651698-A | Pyridone MK2 inhibitors and uses thereof | 新特拉有限公司 | 2024-03-05 | — | — | CN | disclosed |