Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26613698 | 0.85 | L3MBTL1 (0.42) | MAPTRAB9AKDM4EALOX15L3MBTL1 | |
| SCHEMBL29882320 | 0.84 | BRD4 (0.46) | BRD4MAPTNPC1LMNARAB9A | |
| SCHEMBL29199459 | 0.81 | BRD4 (0.49) | BRD4MAPTNPC1LMNARAB9A | |
| SCHEMBL3369457 | 0.79 | BRD4 (0.57) | BRD4MAPTNPC1RAB9AKDM4E | |
| SCHEMBL25227115 | 0.77 | MAPT (0.51) | BRD4MAPTNPC1LMNARAB9A | |
| SCHEMBL22395439 | 0.76 | BRD4 (0.47) | BRD4MAPTNPC1LMNARAB9A | |
| SCHEMBL29272499 | 0.75 | KDM4E (0.44) | BRD4MAPTNPC1LMNARAB9A | |
| SCHEMBL14941222 | 0.75 | TSHR (0.50) | LMNAKDM4ECYP1A2CYP4F2CYP4A11 | |
| SCHEMBL28337899 | 0.75 | BRD4 (0.49) | BRD4MAPTNPC1LMNARAB9A | |
| SCHEMBL9434187 | 0.75 | BRD4 (0.49) | BRD4MAPTNPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119451961-A | Carboxamide derivative with RSK inhibition effect, pharmaceutical composition containing carboxamide derivative and application of carboxamide derivative | 广州科恩泰生物医药科技有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-117186098-A | Carboxamide derivative with RSK inhibition effect, pharmaceutical composition containing carboxamide derivative and application of carboxamide derivative | 上海科恩泰生物医药科技有限公司 | 2023-12-08 | — | — | CN | disclosed |