Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | RARB | P10826 | 9/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | RARA | P10276 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.50 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL28005583 | 1.00 | TP53 (0.57) | TP53TSHRRARBPLA2G4BMEN1 | |
| Terephthalic Acid SCHEMBL30402864 | 1.00 | TP53 (0.57) | TP53TSHRRARBPLA2G4BMEN1 | |
| Terephthalic Acid SCHEMBL8840756 | 0.98 | RARB (0.54) | TP53TSHRRARBPLA2G4BMEN1 | |
| Terephthalic Acid SCHEMBL11562692 | 0.98 | RARB (0.54) | TP53TSHRRARBPLA2G4BMEN1 | |
| Terephthalic Acid SCHEMBL28910481 | 0.95 | TP53 (0.53) | TP53TSHRRARBPLA2G4BMEN1 | |
| Benzoic Acid SCHEMBL28954695 | 0.93 | CES2 (0.51) | TP53TSHRRARBPLA2G4BMEN1 | |
| Benzoic Acid SCHEMBL27642010 | 0.93 | CES2 (0.51) | TP53TSHRRARBPLA2G4BMEN1 | |
| Benzoic Acid SCHEMBL28107042 | 0.93 | CES2 (0.51) | TP53TSHRRARBPLA2G4BMEN1 | |
| Benzoic Acid SCHEMBL27624637 | 0.93 | CES2 (0.51) | TP53TSHRRARBPLA2G4BMEN1 | |
| Terephthalic Acid SCHEMBL28532097 | 0.93 | RARB (0.50) | TP53TSHRRARBPLA2G4BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946649-A | Sustained-release foam discharging agent and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-116774542-A | Toner containing charge control agent | 施乐公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-116194808-A | Removal of color from polymeric materials | 美国阿拉丁制造公司 | 2023-05-30 | — | — | CN | disclosed |