Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PSIP1 | O75475 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RORA | P35398 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17720261 | 1.00 | GAA (0.47) | GAAPSIP1ABCB11MEN1KMT2A | |
| SCHEMBL17716833 | 0.85 | GAA (0.44) | GAAPSIP1MEN1KMT2ARORC | |
| SCHEMBL6679380 | 0.84 | GAA (0.46) | GAAABCB11ALDH1A1TRPA1KDM4E | |
| SCHEMBL10179790 | 0.84 | PSIP1 (0.50) | GAAPSIP1MEN1KMT2AALDH1A1 | |
| SCHEMBL28631313 | 0.81 | GAA (0.47) | GAAPSIP1MEN1KMT2ARORC | |
| SCHEMBL16232116 | 0.80 | GAA (0.55) | GAAPSIP1MEN1KMT2ARORC | |
| SCHEMBL30026174 | 0.80 | PSIP1 (0.50) | GAAPSIP1MEN1KMT2ARORC | |
| SCHEMBL18440551 | 0.80 | GAA (0.55) | GAAPSIP1MEN1KMT2ARORC | |
| SCHEMBL10180779 | 0.79 | GAA (0.59) | GAAPSIP1MEN1KMT2ARORC | |
| SCHEMBL23636873 | 0.79 | GAA (0.46) | GAAPSIP1KMT2ARORCRORA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |