Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | F2R | P25116 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28534685 | 0.80 | P2RY14 (0.45) | NOTUMP2RY14 | |
| SCHEMBL28527120 | 0.75 | KDM4E (0.46) | NOTUMF2RPROKR1KDM4EALDH1A1 | |
| Formamide SCHEMBL23632185 | 0.75 | F2R (0.43) | F2RHTR2CPROKR1KDM4EALDH1A1 | |
| SCHEMBL28532704 | 0.74 | HSD11B1 (0.46) | NOTUMF2RHTR2CP2RY14 | |
| SCHEMBL23632041 | 0.74 | HSD11B1 (0.46) | NOTUMF2RHTR2CP2RY14 | |
| SCHEMBL1580970 | 0.72 | NOTUM (0.47) | NOTUMF2RHTR2CPROKR1P2RY14 | |
| SCHEMBL21616642 | 0.72 | SRD5A2 (0.48) | F2RP2RY14KDM4EALDH1A1POLB | |
| SCHEMBL30474539 | 0.72 | EPHX2 (0.40) | F2RPROKR1KDM4EALDH1A1POLB | |
| SCHEMBL31154255 | 0.72 | AKR1C3 (0.65) | NOTUMF2RHTR2CP2RY14KDM4E | |
| SCHEMBL23632103 | 0.71 | HTR2C (0.44) | NOTUMF2RHTR2CPROKR1P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |