Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.67 |
| ▸ | HPGD | P15428 | 7/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | CA2 | P00918 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.67 |
| ▸ | CA1 | P00915 | 1/20 | 0.67 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.67 |
| ▸ | CA4 | P22748 | 1/20 | 0.67 |
| ▸ | CA6 | P23280 | 1/20 | 0.67 |
| ▸ | CA7 | P43166 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | CA9 | Q16790 | 1/20 | 0.67 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.67 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL27672324 | 0.89 | ALDH1A1 (0.67) | ALDH1A1HPGDKDM4ETSHRCA2 | |
| Benzene SCHEMBL28042782 | 0.84 | ALDH1A1 (0.95) | ALDH1A1HPGDKDM4ETSHRCA2 | |
| SCHEMBL23542116 | 0.84 | ALDH1A1 (0.95) | ALDH1A1HPGDKDM4ETSHRCA2 | |
| Tert-Butylbenzene SCHEMBL17156442 | 0.83 | ALDH1A1 (0.69) | ALDH1A1HPGDKDM4ETSHRCA2 | |
| SCHEMBL31028133 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HPGDKDM4ETSHRCA2 | |
| SCHEMBL39249 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HPGDKDM4ETSHRCA2 | |
| Salicylic Acid SCHEMBL28310475 | 0.82 | ALDH1A1 (0.90) | ALDH1A1HPGDKDM4ETSHRCA2 | |
| Salicylic Acid SCHEMBL8029424 | 0.82 | ALDH1A1 (0.90) | ALDH1A1HPGDKDM4ETSHRCA2 | |
| Salicylic Acid SCHEMBL29555395 | 0.82 | ALDH1A1 (0.90) | ALDH1A1HPGDKDM4ETSHRCA2 | |
| Salicylic Acid SCHEMBL1509155 | 0.82 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4ETSHRCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986765-A | Flame-retardant polyvinyl chloride cable material and preparation method thereof | 江苏东旭电缆有限公司 | 2024-05-07 | — | — | CN | claimed |
| CN-119331318-A | Self-sealing sizing material composition, self-sealing sizing material, preparation method and application thereof | 赛轮集团股份有限公司 | 2025-01-21 | — | — | CN | disclosed |
| CN-117986765-A | Flame-retardant polyvinyl chloride cable material and preparation method thereof | 江苏东旭电缆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-117802632-A | Special oiling agent for elasticized polyester FDY filaments and preparation method thereof | 江苏恒科新材料有限公司 | 2024-04-02 | — | — | CN | disclosed |