Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.69 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30802615 | 1.00 | PARP1 (0.69) | PARP1PARP2RAB9ANPC1MAPT | |
| SCHEMBL29200316 | 0.86 | PARP1 (0.63) | PARP1PARP2RAB9ANPC1MAPT | |
| SCHEMBL29200349 | 0.85 | PARP1 (0.83) | PARP1PARP2RAB9ANPC1MAPT | |
| SCHEMBL30802658 | 0.85 | PARP1 (0.83) | PARP1PARP2RAB9ANPC1MAPT | |
| SCHEMBL30802656 | 0.84 | PARP1 (0.76) | PARP1PARP2RAB9ANPC1MAPT | |
| SCHEMBL29200363 | 0.84 | PARP1 (0.77) | PARP1PARP2RAB9ANPC1MAPT | |
| SCHEMBL29200327 | 0.84 | PARP1 (0.76) | PARP1PARP2RAB9ANPC1MAPT | |
| SCHEMBL30802617 | 0.84 | PARP1 (0.77) | PARP1PARP2RAB9ANPC1MAPT | |
| SCHEMBL29200339 | 0.83 | PARP1 (0.78) | PARP1PARP2RAB9ANPC1MAPT | |
| SCHEMBL29200335 | 0.83 | PARP1 (0.76) | PARP1PARP2RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658868-A | Benzamide derivative and preparation method and application thereof | 中山大学 | 2024-03-08 | — | — | CN | claimed |
| CN-117658868-A | Benzamide derivative and preparation method and application thereof | 中山大学 | 2024-03-08 | — | — | CN | disclosed |