Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | RNF4 | P78317 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30802615 | 0.86 | PARP1 (0.69) | PARP1RAB9ANPC1MAPTCASP3 | |
| SCHEMBL29200312 | 0.86 | PARP1 (0.69) | PARP1RAB9ANPC1MAPTCASP3 | |
| SCHEMBL29200362 | 0.84 | PARP1 (0.66) | PARP1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL29200344 | 0.79 | PPIA (0.65) | PARP1RAB9ANPC1MAPTCASP3 | |
| SCHEMBL30802647 | 0.79 | PPIA (0.65) | PARP1RAB9ANPC1MAPTCASP3 | |
| SCHEMBL718082 | 0.79 | PARP1 (0.79) | PARP1NPC1MAPTSGMS2GAA | |
| SCHEMBL29200326 | 0.76 | PARP1 (0.85) | PARP1RAB9ANPC1MAPTSGMS2 | |
| SCHEMBL29200330 | 0.76 | PARP1 (0.65) | PARP1RAB9ANPC1MAPTSGMS2 | |
| SCHEMBL30802630 | 0.76 | PARP1 (0.65) | PARP1RAB9ANPC1MAPTSGMS2 | |
| SCHEMBL3224230 | 0.75 | LTA4H (0.76) | RAB9ANPC1LMNASMN1; SMN2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658868-A | Benzamide derivative and preparation method and application thereof | 中山大学 | 2024-03-08 | — | — | CN | claimed |
| CN-117658868-A | Benzamide derivative and preparation method and application thereof | 中山大学 | 2024-03-08 | — | — | CN | disclosed |