Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 1.00 |
| ▸ | AURKA | O14965 | 9/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 8/20 | 0.54 |
| ▸ | RPS6KB1 | P23443 | 8/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30802645 | 1.00 | PARP1 (1.00) | PARP1AURKAAURKBRPS6KB1KDM4E | |
| Hydrochloric Acid SCHEMBL29200394 | 0.99 | PARP1 (0.98) | PARP1AURKAAURKBRPS6KB1KDM4E | |
| Hydrochloric Acid SCHEMBL30802688 | 0.99 | PARP1 (0.98) | PARP1AURKAAURKBRPS6KB1KDM4E | |
| SCHEMBL30802620 | 0.92 | PARP1 (0.85) | PARP1AURKAAURKBRPS6KB1KDM4E | |
| SCHEMBL29200336 | 0.92 | PARP1 (0.85) | PARP1AURKAAURKBRPS6KB1KDM4E | |
| SCHEMBL29200364 | 0.90 | PARP1 (0.82) | PARP1AURKAAURKBRPS6KB1KDM4E | |
| SCHEMBL30802652 | 0.90 | PARP1 (0.82) | PARP1AURKAAURKBRPS6KB1KDM4E | |
| SCHEMBL29200350 | 0.87 | PARP1 (0.78) | PARP1AURKAAURKBRPS6KB1MEN1 | |
| SCHEMBL30802640 | 0.87 | PARP1 (0.78) | PARP1AURKAAURKBRPS6KB1SIRT2 | |
| SCHEMBL29200348 | 0.87 | PARP1 (0.77) | PARP1KDM4EMEN1KMT2ASIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658868-A | Benzamide derivative and preparation method and application thereof | 中山大学 | 2024-03-08 | — | — | CN | claimed |
| CN-117658868-A | Benzamide derivative and preparation method and application thereof | 中山大学 | 2024-03-08 | — | — | CN | disclosed |