Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.82 |
| ▸ | AURKA | O14965 | 9/20 | 0.64 |
| ▸ | RPS6KB1 | P23443 | 9/20 | 0.64 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.57 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30802652 | 1.00 | PARP1 (0.82) | PARP1AURKARPS6KB1AURKBKDM4E | |
| SCHEMBL29200324 | 0.90 | PARP1 (1.00) | PARP1AURKARPS6KB1AURKBKDM4E | |
| SCHEMBL30802645 | 0.90 | PARP1 (1.00) | PARP1AURKARPS6KB1AURKBKDM4E | |
| SCHEMBL29200323 | 0.90 | PARP1 (0.75) | PARP1AURKARPS6KB1AURKBKDM4E | |
| SCHEMBL30802613 | 0.90 | MEN1 (0.75) | PARP1AURKARPS6KB1AURKBKDM4E | |
| SCHEMBL30802642 | 0.90 | PARP1 (0.75) | PARP1AURKARPS6KB1AURKBKDM4E | |
| SCHEMBL30802646 | 0.90 | PARP1 (0.75) | PARP1AURKARPS6KB1AURKBKDM4E | |
| SCHEMBL29200319 | 0.90 | MEN1 (0.75) | PARP1AURKARPS6KB1AURKBKDM4E | |
| SCHEMBL29200370 | 0.90 | PARP1 (0.75) | PARP1AURKARPS6KB1AURKBKDM4E | |
| Hydrochloric Acid SCHEMBL29200394 | 0.89 | PARP1 (0.98) | PARP1AURKARPS6KB1AURKBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658868-A | Benzamide derivative and preparation method and application thereof | 中山大学 | 2024-03-08 | — | — | CN | claimed |
| CN-117658868-A | Benzamide derivative and preparation method and application thereof | 中山大学 | 2024-03-08 | — | — | CN | disclosed |