Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.74 |
| ▸ | NPC1 | O15118 | 3/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | TP53 | P04637 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.62 |
| ▸ | AURKA | O14965 | 1/20 | 0.59 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.59 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.59 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30802623 | 1.00 | PARP1 (0.74) | PARP1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL30802627 | 0.92 | SMN1; SMN2 (0.67) | PARP1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL29200329 | 0.92 | SMN1; SMN2 (0.67) | PARP1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL29200349 | 0.90 | PARP1 (0.83) | PARP1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL30802658 | 0.90 | PARP1 (0.83) | PARP1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL30802629 | 0.88 | PARP1 (0.76) | PARP1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL29200313 | 0.88 | PARP1 (0.76) | PARP1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL30802636 | 0.86 | MAPT (0.65) | PARP1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL29200327 | 0.85 | PARP1 (0.76) | PARP1NPC1RAB9AMAPTPARP2 | |
| SCHEMBL30802644 | 0.85 | PARP1 (0.76) | PARP1PARP2AURKARPS6KB1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658868-A | Benzamide derivative and preparation method and application thereof | 中山大学 | 2024-03-08 | — | — | CN | claimed |
| CN-117658868-A | Benzamide derivative and preparation method and application thereof | 中山大学 | 2024-03-08 | — | — | CN | disclosed |