Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | NPC1 | O15118 | 5/20 | 0.67 |
| ▸ | RAB9A | P51151 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | TP53 | P04637 | 3/20 | 0.67 |
| ▸ | PARP1 | P09874 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.53 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30802627 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9AMAPTTP53 | |
| SCHEMBL29200380 | 0.92 | PARP1 (0.74) | SMN1; SMN2NPC1RAB9AMAPTTP53 | |
| SCHEMBL30802623 | 0.92 | PARP1 (0.74) | SMN1; SMN2NPC1RAB9AMAPTTP53 | |
| SCHEMBL29200330 | 0.88 | PARP1 (0.65) | SMN1; SMN2NPC1RAB9AMAPTTP53 | |
| SCHEMBL30802654 | 0.88 | PARP1 (0.65) | SMN1; SMN2NPC1RAB9AMAPTTP53 | |
| SCHEMBL29200362 | 0.87 | PARP1 (0.66) | NPC1RAB9APARP1MEN1KMT2A | |
| SCHEMBL30802625 | 0.86 | PARP1 (0.85) | SMN1; SMN2NPC1RAB9AMAPTTP53 | |
| SCHEMBL29200326 | 0.86 | PARP1 (0.85) | SMN1; SMN2NPC1RAB9AMAPTTP53 | |
| SCHEMBL29200328 | 0.86 | PARP1 (0.65) | NPC1RAB9AMAPTPARP1MEN1 | |
| SCHEMBL30802630 | 0.86 | PARP1 (0.65) | NPC1RAB9AMAPTPARP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658868-A | Benzamide derivative and preparation method and application thereof | 中山大学 | 2024-03-08 | — | — | CN | claimed |
| CN-117658868-A | Benzamide derivative and preparation method and application thereof | 中山大学 | 2024-03-08 | — | — | CN | disclosed |