Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | KCNJ5 | P48544 | 4/20 | 0.52 |
| ▸ | KCNJ3 | P48549 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.51 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.50 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30802689 | 1.00 | CA12 (0.53) | CA12CA1CA2CA9KCNJ5 | |
| SCHEMBL4717808 | 0.88 | CA12 (0.54) | CA12CA1CA2CA9KCNJ5 | |
| SCHEMBL30802682 | 0.88 | CA12 (0.54) | CA12CA1CA2CA9KCNJ5 | |
| SCHEMBL29200411 | 0.85 | KCNJ5 (0.72) | KCNJ5KCNJ3KMT2AMEN1LMNA | |
| SCHEMBL30802695 | 0.85 | KCNJ5 (0.72) | KCNJ5KCNJ3KMT2AMEN1LMNA | |
| SCHEMBL28762298 | 0.81 | CA12 (0.70) | CA12CA1CA2CA9KCNJ5 | |
| SCHEMBL29200447 | 0.81 | KMT2A (0.57) | KMT2AMEN1LMNAGAAALDH1A1 | |
| SCHEMBL30802694 | 0.81 | KMT2A (0.57) | KMT2AMEN1LMNAGAAALDH1A1 | |
| SCHEMBL29200430 | 0.81 | KMT2A (0.72) | KMT2AMEN1LMNAGAAALDH1A1 | |
| SCHEMBL30802660 | 0.81 | KMT2A (0.72) | KMT2AMEN1LMNAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658868-A | Benzamide derivative and preparation method and application thereof | 中山大学 | 2024-03-08 | — | — | CN | disclosed |