Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ5 | P48544 | 7/20 | 0.72 |
| ▸ | KCNJ3 | P48549 | 7/20 | 0.72 |
| ▸ | KCNJ6 | P48051 | 3/20 | 0.64 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | CLK2 | P49760 | 1/20 | 0.53 |
| ▸ | PRKX | P51817 | 1/20 | 0.53 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.53 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.53 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30802695 | 1.00 | KCNJ5 (0.72) | KCNJ5KCNJ3KCNJ6ACKR3NR1I2 | |
| SCHEMBL29200421 | 0.89 | KCNJ5 (0.72) | KCNJ5KCNJ3KCNJ6ACKR3NR1I2 | |
| SCHEMBL30802690 | 0.89 | KCNJ5 (0.72) | KCNJ5KCNJ3KCNJ6ACKR3NR1I2 | |
| SCHEMBL30802689 | 0.85 | CA12 (0.53) | KCNJ5KCNJ3KCNJ6LMNAALDH1A1 | |
| SCHEMBL29200401 | 0.85 | CA12 (0.53) | KCNJ5KCNJ3KCNJ6LMNAALDH1A1 | |
| SCHEMBL31729852 | 0.82 | KCNJ5 (0.74) | KCNJ5KCNJ3KCNJ6CLK2PRKX | |
| SCHEMBL30802681 | 0.80 | MEN1 (0.66) | KCNJ5KCNJ3ACKR3ALDH1A1MEN1 | |
| SCHEMBL29200352 | 0.80 | NLRP3 (0.72) | KCNJ5KCNJ3KCNJ6LMNAALDH1A1 | |
| SCHEMBL29200413 | 0.80 | MEN1 (0.66) | KCNJ5KCNJ3ACKR3ALDH1A1MEN1 | |
| SCHEMBL30802669 | 0.80 | NLRP3 (0.72) | KCNJ5KCNJ3KCNJ6LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658868-A | Benzamide derivative and preparation method and application thereof | 中山大学 | 2024-03-08 | — | — | CN | disclosed |