Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAK | O14976 | 3/20 | 0.61 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.52 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.52 |
| ▸ | EPHA8 | P29322 | 1/20 | 0.52 |
| ▸ | TXK | P42681 | 1/20 | 0.52 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.52 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 3/20 | 0.47 |
| ▸ | GSK3A | P49840 | 3/20 | 0.47 |
| ▸ | GSK3B | P49841 | 3/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29089850 | 0.86 | GAK (0.65) | GAKRIPK2EPHB6ABL1LCK | |
| SCHEMBL29200458 | 0.86 | GAK (0.64) | GAKRIPK2EPHB6ABL1LCK | |
| SCHEMBL28845654 | 0.83 | GAK (0.58) | GAKRIPK2EPHB6ABL1LCK | |
| SCHEMBL10664310 | 0.82 | GAK (0.57) | GAKRIPK2EPHB6ABL1LCK | |
| SCHEMBL29822705 | 0.81 | GAK (0.56) | GAKRIPK2EPHB6ABL1LCK | |
| Hydrochloric Acid SCHEMBL10673049 | 0.81 | GAK (0.56) | GAKRIPK2EPHB6ABL1LCK | |
| Hydrochloric Acid SCHEMBL11523664 | 0.81 | GAK (0.56) | GAKRIPK2EPHB6ABL1LCK | |
| SCHEMBL5929021 | 0.81 | MAPT (0.69) | GAKGAAMAPTATMKDR | |
| SCHEMBL5929206 | 0.81 | GAK (0.58) | GAKRIPK2EPHB6ABL1LCK | |
| Hydrochloric Acid SCHEMBL11738528 | 0.80 | GAK (0.55) | GAKRIPK2EPHB6ABL1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773267-B | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2024-01-26 | — | — | CN | claimed |