Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.70 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.70 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | ABL1 | P00519 | 1/20 | 0.61 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | STS | P08842 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6313737 | 0.85 | EPHX2 (0.68) | PTPN2PTPN1PTPN6NPC1RAB9A | |
| SCHEMBL3557554 | 0.85 | PTPN2 (0.81) | PTPN2PTPN1PTPN6NPC1RAB9A | |
| SCHEMBL27008592 | 0.85 | PTPN2 (0.62) | PTPN2PTPN1PTPN6NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL28768913 | 0.84 | PTPN2 (0.79) | PTPN2PTPN1PTPN6NPC1RAB9A | |
| SCHEMBL889067 | 0.84 | PTPN2 (0.60) | PTPN2PTPN1PTPN6NPC1RAB9A | |
| SCHEMBL28898378 | 0.83 | PTPN1 (0.90) | PTPN2PTPN1PTPN6NPC1RAB9A | |
| SCHEMBL13676224 | 0.82 | PTPN2 (0.68) | PTPN2PTPN1PTPN6NPC1RAB9A | |
| SCHEMBL1946598 | 0.82 | PTPN2 (0.72) | PTPN2PTPN1PTPN6NPC1RAB9A | |
| SCHEMBL3050576 | 0.82 | PTPN2 (0.65) | PTPN2PTPN1PTPN6NPC1RAB9A | |
| SCHEMBL3046664 | 0.82 | PTPN2 (0.65) | PTPN2PTPN1PTPN6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658992-A | Benzimidazole compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2024-03-08 | — | — | CN | disclosed |