Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | BPTF | Q12830 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30803057 | 1.00 | MAPT (0.46) | MAPTSMN1; SMN2ALDH1A1BPTFPOLB | |
| SCHEMBL7373096 | 0.78 | TSHR (0.59) | MAPTSMN1; SMN2ALDH1A1BPTFPOLB | |
| SCHEMBL30283302 | 0.78 | TSHR (0.59) | MAPTSMN1; SMN2ALDH1A1BPTFPOLB | |
| SCHEMBL19436450 | 0.76 | MAPT (0.50) | MAPTSMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL23077561 | 0.76 | TTR (0.51) | MAPTSMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL28154683 | 0.74 | HTT (0.46) | MAPTSMN1; SMN2ALDH1A1TDP1CYP3A4 | |
| SCHEMBL22121409 | 0.74 | PRSS1 (0.48) | MAPTSMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL22121138 | 0.73 | MAPT (0.39) | MAPTSMN1; SMN2ALDH1A1BPTFPOLB | |
| SCHEMBL20066389 | 0.73 | PRSS1 (0.50) | MAPTSMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL30947784 | 0.73 | MAPT (0.47) | MAPTSMN1; SMN2ALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658992-A | Benzimidazole compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2024-03-08 | — | — | CN | disclosed |