Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29240413 | 1.00 | MAPT (0.47) | MAPTALDH1A1SMN1; SMN2POLBTDP1 | |
| SCHEMBL29577441 | 0.87 | VCAM1 (0.48) | MAPTALDH1A1POLBTDP1TSHR | |
| SCHEMBL15552087 | 0.87 | TPMT (0.55) | MAPTALDH1A1SMN1; SMN2TDP1TSHR | |
| SCHEMBL29847250 | 0.87 | TPMT (0.55) | MAPTALDH1A1SMN1; SMN2TDP1TSHR | |
| SCHEMBL16841183 | 0.87 | LMNA (0.47) | MAPTALDH1A1SMN1; SMN2POLBTDP1 | |
| SCHEMBL15551607 | 0.87 | VCAM1 (0.48) | MAPTALDH1A1POLBTDP1TSHR | |
| SCHEMBL21295074 | 0.86 | ALDH1A1 (0.43) | MAPTALDH1A1SMN1; SMN2POLBTDP1 | |
| SCHEMBL29847044 | 0.86 | ALDH1A1 (0.43) | MAPTALDH1A1SMN1; SMN2POLBTDP1 | |
| SCHEMBL19437401 | 0.83 | MAPT (0.51) | MAPTALDH1A1SMN1; SMN2TDP1HTT | |
| SCHEMBL7373096 | 0.82 | TSHR (0.59) | MAPTALDH1A1SMN1; SMN2POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118265545-A | Asymmetric bisbenzimidazole STING agonist immunoconjugates and uses thereof | 博尔特生物治疗药物有限公司 | 2024-06-28 | — | — | CN | disclosed |