Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.59 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CCR2 | P41597 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30783435 | 1.00 | MAPK14 (0.59) | MAPK14P2RX4KMT2AKDM4EMEN1 | |
| SCHEMBL30783430 | 0.80 | KMT2A (0.70) | P2RX4KMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL29200844 | 0.80 | KMT2A (0.70) | P2RX4KMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL4069762 | 0.75 | CFTR (0.47) | P2RX4KMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL10642119 | 0.74 | KMT2A (0.64) | P2RX4KMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL11296345 | 0.73 | MAPK14 (0.47) | MAPK14KMT2AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL30783405 | 0.71 | MEN1 (0.55) | P2RX4KMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL29200804 | 0.71 | MEN1 (0.55) | P2RX4KMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL2260831 | 0.70 | GSK3A (0.48) | P2RX4KMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL21023182 | 0.70 | P2RX4 (0.53) | P2RX4KMT2AKDM4EMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624043-A | Preparation method of quinolinone compound | 安徽中医药大学 | 2024-03-01 | — | — | CN | disclosed |