Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30783430 | 1.00 | KMT2A (0.70) | KMT2AMEN1ATMP2RX4MAPT | |
| SCHEMBL30783416 | 0.83 | MEN1 (1.00) | KMT2AMEN1ATMP2RX4MAPT | |
| SCHEMBL377486 | 0.83 | MEN1 (1.00) | KMT2AMEN1ATMP2RX4MAPT | |
| SCHEMBL30783426 | 0.81 | KMT2A (0.61) | KMT2AMEN1ATMP2RX4MAPT | |
| SCHEMBL29200808 | 0.81 | KMT2A (0.61) | KMT2AMEN1ATMP2RX4MAPT | |
| SCHEMBL29200848 | 0.80 | MAPK14 (0.59) | KMT2AMEN1P2RX4MAPTKDM4E | |
| SCHEMBL30783435 | 0.80 | MAPK14 (0.59) | KMT2AMEN1P2RX4MAPTKDM4E | |
| SCHEMBL14529788 | 0.78 | SMN1; SMN2 (0.65) | KMT2AMEN1ATMP2RX4MAPT | |
| SCHEMBL4096894 | 0.77 | KDM4E (0.43) | KMT2AMEN1ATMKDM4EALDH1A1 | |
| SCHEMBL29200792 | 0.77 | KMT2A (0.56) | KMT2AMEN1ATMP2RX4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624043-A | Preparation method of quinolinone compound | 安徽中医药大学 | 2024-03-01 | — | — | CN | disclosed |