Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.55 |
| ▸ | MPO | P05164 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ECE1 | P42892 | 5/20 | 0.44 |
| ▸ | CTSC | P53634 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dl-Tryptophan SCHEMBL28481662 | 0.93 | KDM4E (0.64) | KDM4EMAPTKMT2AMEN1LMNA | |
| Tryptophan SCHEMBL9551469 | 0.93 | KDM4E (0.53) | KDM4EMAPTKMT2AMEN1LMNA | |
| Dl-Tryptophan SCHEMBL29253127 | 0.88 | KDM4E (0.71) | KDM4EMAPTKMT2AMEN1LMNA | |
| Tryptophan SCHEMBL17503874 | 0.88 | KDM4E (0.71) | KDM4EMAPTKMT2AMEN1LMNA | |
| D-Tryptophan SCHEMBL14691185 | 0.88 | KDM4E (0.57) | KDM4EMAPTKMT2AMEN1LMNA | |
| Tryptophan SCHEMBL7154073 | 0.86 | KDM4E (0.74) | KDM4EMAPTKMT2AMEN1LMNA | |
| Dl-Tryptophan SCHEMBL7859113 | 0.86 | KDM4E (0.74) | KDM4EMAPTKMT2AMEN1LMNA | |
| Dl-Tryptophan SCHEMBL634683 | 0.86 | KMT2A (0.74) | KDM4EMAPTKMT2AMEN1LMNA | |
| Dl-Tryptophan SCHEMBL28059654 | 0.86 | KMT2A (0.74) | KDM4EMAPTKMT2AMEN1LMNA | |
| Dl-Tryptophan SCHEMBL28149832 | 0.86 | KMT2A (0.74) | KDM4EMAPTKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117660354-A | Modified extracellular vesicles of specific targeted kidney as well as preparation method and application thereof | 武汉大学中南医院 | 2024-03-08 | — | — | CN | disclosed |