Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 6/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20581341 | 0.83 | RAB9A (0.60) | MIFRAB9ASMN1; SMN2NPC1RECQL | |
| SCHEMBL29401442 | 0.83 | RAB9A (0.60) | MIFRAB9ASMN1; SMN2NPC1RECQL | |
| SCHEMBL6444640 | 0.81 | MIF (1.00) | MIFRAB9ASMN1; SMN2NPC1RECQL | |
| SCHEMBL6444643 | 0.81 | MIF (1.00) | MIFRAB9ASMN1; SMN2NPC1RECQL | |
| SCHEMBL13401232 | 0.79 | MIF (0.78) | MIFRAB9ASMN1; SMN2NPC1RECQL | |
| SCHEMBL21847106 | 0.78 | RAB9A (1.00) | MIFRAB9ASMN1; SMN2NPC1RECQL | |
| SCHEMBL13401226 | 0.78 | RAB9A (1.00) | MIFRAB9ASMN1; SMN2NPC1RECQL | |
| SCHEMBL21914676 | 0.78 | RAB9A (1.00) | MIFRAB9ASMN1; SMN2NPC1RECQL | |
| SCHEMBL21847176 | 0.78 | CYP1A2 (0.51) | MIFKMT2ALMNAPOLBMEN1 | |
| SCHEMBL28371327 | 0.78 | CYP1A2 (0.51) | MIFKMT2ALMNAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110914280-B | 6H-thieno [2,3-e ] [1,2,4] triazolo [3,4-c ] [1,2,4] triazab derivatives | 阿尤米制药公司 | 2024-05-03 | — | — | CN | disclosed |