Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 6/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29286890 | 0.90 | USP2 (0.41) | NR1H2USP2SMN1; SMN2ESR2ADORA1 | |
| SCHEMBL27660306 | 0.87 | NR1H2 (0.44) | NR1H2USP2SMN1; SMN2ESR2ADORA1 | |
| SCHEMBL15749495 | 0.81 | NR1H2 (0.43) | NR1H2USP2SMN1; SMN2ESR2ADORA1 | |
| SCHEMBL30075744 | 0.81 | NR1H2 (0.43) | NR1H2USP2SMN1; SMN2ESR2ADORA1 | |
| SCHEMBL518157 | 0.74 | USP2 (0.42) | NR1H2USP2SMN1; SMN2ESR2ADORA1 | |
| SCHEMBL21098079 | 0.73 | USP2 (0.47) | NR1H2USP2SMN1; SMN2ALDH1A1LMNA | |
| Water SCHEMBL26621617 | 0.72 | USP2 (0.41) | NR1H2USP2SMN1; SMN2ESR2ADORA1 | |
| SCHEMBL29440339 | 0.72 | USP2 (0.41) | NR1H2USP2SMN1; SMN2ESR2ADORA1 | |
| SCHEMBL14795217 | 0.72 | USP2 (0.51) | NR1H2USP2SMN1; SMN2ESR2ADORA1 | |
| SCHEMBL517374 | 0.72 | NR1H2 (0.46) | NR1H2USP2SMN1; SMN2ESR2ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393916-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |
| CN-117813299-A | Nitrogen-containing heterocyclic derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-04-02 | — | — | CN | disclosed |