Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156576 | 0.83 | NR1H2 (0.45) | USP2SMN1; SMN2ESR2NR1H2DDB1 | |
| SCHEMBL518157 | 0.83 | USP2 (0.42) | USP2SMN1; SMN2ESR2NR1H2DDB1 | |
| Water SCHEMBL26621617 | 0.82 | USP2 (0.41) | USP2SMN1; SMN2ESR2NR1H2DDB1 | |
| SCHEMBL29286890 | 0.82 | USP2 (0.41) | USP2SMN1; SMN2ESR2NR1H2DDB1 | |
| SCHEMBL29116107 | 0.79 | USP30 (0.46) | USP2SMN1; SMN2ESR2NR1H2DDB1 | |
| SCHEMBL30774901 | 0.79 | RORC (0.40) | USP2SMN1; SMN2ESR2NR1H2DDB1 | |
| SCHEMBL18297062 | 0.78 | USP2 (0.39) | USP2SMN1; SMN2ESR2NR1H2DDB1 | |
| SCHEMBL18280996 | 0.78 | USP2 (0.39) | USP2SMN1; SMN2ESR2NR1H2DDB1 | |
| SCHEMBL18280999 | 0.78 | USP2 (0.39) | USP2SMN1; SMN2ESR2NR1H2DDB1 | |
| SCHEMBL27143468 | 0.77 | EPHX2 (0.39) | USP2SMN1; SMN2ESR2NR1H2DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206872-A | Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR8 agonists | 百济神州有限公司 | 2022-03-18 | — | — | CN | disclosed |