SCHEMBL29201280

SCHEMBL29201280

C=C(CCN(C)C)C(=O)OCCC=C(C)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM5 P08912 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRNB2 P17787 1/20 0.32
CHRM3 P20309 1/20 0.32
CHRNA4 P43681 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27853786 0.92 TSHR (0.35) CYP2D6
SCHEMBL11598897 0.83 CYP2D6 (0.34) CYP2D6CYP2C19
SCHEMBL27835757 0.82 USP2 (0.33) CYP2D6CYP2C19
SCHEMBL14992900 0.81 CD81 (0.31)
SCHEMBL8003904 0.81 CHRM1 (0.40) CYP2C19CHRM2CHRM4CHRM5CHRM1
SCHEMBL6638068 0.80 CYP2D6 (0.38) CYP2D6CYP2C19
SCHEMBL27219664 0.80 CYP2D6 (0.35) CYP2D6CYP2C19
SCHEMBL8736372 0.80 CHRM2 (0.36) CYP2C19CHRM2CHRM4CHRM5CHRM1
SCHEMBL29664602 0.79 THRB (0.39) CHRM2CHRM4CHRM5CHRM1CHRNB2
SCHEMBL6547117 0.79 THRB (0.47) CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114681324-B Double-release dosage form capsule and preparation method, device and system thereof 盖尔凯普科技有限公司 2024-05-03 CN disclosed