Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 16/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21722399 | 1.00 | CYP19A1 (0.48) | CYP19A1CYP1A1FOLH1LMNAMAPT | |
| SCHEMBL28468849 | 1.00 | CYP19A1 (0.48) | CYP19A1CYP1A1FOLH1LMNAMAPT | |
| SCHEMBL28631351 | 0.83 | CYP19A1 (0.45) | CYP19A1CYP1A1FOLH1 | |
| SCHEMBL28631352 | 0.83 | CYP19A1 (0.45) | CYP19A1CYP1A1FOLH1 | |
| SCHEMBL28918868 | 0.81 | CYP19A1 (0.43) | CYP19A1CYP1A1FOLH1 | |
| SCHEMBL28469268 | 0.78 | CYP19A1 (0.41) | CYP19A1CYP1A1FOLH1 | |
| SCHEMBL28466830 | 0.78 | CYP19A1 (0.41) | CYP19A1CYP1A1FOLH1 | |
| SCHEMBL28472198 | 0.73 | LMNA (0.47) | LMNAMAPTCHRM2CHRM4CHRM5 | |
| SCHEMBL28472196 | 0.73 | LMNA (0.47) | LMNAMAPTCHRM2CHRM4CHRM5 | |
| SCHEMBL4485559 | 0.73 | CYP19A1 (0.47) | CYP19A1CYP1A1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181092-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2024-05-03 | — | — | CN | disclosed |