Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 13/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 13/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.35 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28459169 | 0.89 | ADORA2A (0.50) | ADORA2AADORA1TGFBR1TGFBR2NT5E | |
| SCHEMBL21722391 | 0.78 | ADORA2A (0.62) | ADORA2AADORA1 | |
| SCHEMBL28470700 | 0.77 | ADORA2A (0.48) | ADORA2AADORA1 | |
| SCHEMBL22551865 | 0.75 | ADORA2A (0.55) | ADORA2AADORA1TGFBR1TGFBR2 | |
| SCHEMBL30880773 | 0.75 | ADORA2A (0.55) | ADORA2AADORA1TGFBR1TGFBR2 | |
| SCHEMBL28470912 | 0.74 | TDP1 (0.38) | ADORA2A | |
| SCHEMBL29201299 | 0.71 | ADORA2A (0.72) | ADORA2AADORA1 | |
| SCHEMBL22551856 | 0.71 | ADORA2A (0.63) | ADORA2AADORA1TGFBR1TGFBR2 | |
| SCHEMBL29907719 | 0.71 | ADORA2A (0.63) | ADORA2AADORA1TGFBR1TGFBR2 | |
| SCHEMBL21722562 | 0.70 | ADORA2A (0.53) | ADORA2AADORA1TGFBR1TGFBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181092-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2024-05-03 | — | — | CN | disclosed |