Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 16/20 | 0.72 |
| ▸ | ADORA1 | P30542 | 15/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21722538 | 0.84 | ADORA2A (1.00) | ADORA2AADORA1 | |
| SCHEMBL22551962 | 0.84 | ADORA2A (1.00) | ADORA2AADORA1 | |
| SCHEMBL22552053 | 0.84 | ADORA2A (1.00) | ADORA2AADORA1 | |
| SCHEMBL28462557 | 0.84 | ADORA2A (0.58) | ADORA2AADORA1 | |
| SCHEMBL28459169 | 0.81 | ADORA2A (0.50) | ADORA2AADORA1 | |
| SCHEMBL21722364 | 0.81 | ADORA2A (1.00) | ADORA2AADORA1 | |
| SCHEMBL22551783 | 0.81 | ADORA2A (1.00) | ADORA2AADORA1 | |
| SCHEMBL21722873 | 0.81 | ADORA2A (1.00) | ADORA2AADORA1 | |
| SCHEMBL29201321 | 0.80 | ADORA2A (0.48) | ADORA2AADORA1 | |
| SCHEMBL21722339 | 0.80 | ADORA2A (0.96) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181092-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2024-05-03 | — | — | CN | disclosed |