Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 17/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 15/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28460330 | 0.89 | ADORA2A (0.51) | ADORA2AADORA1ADORA2B | |
| SCHEMBL28459119 | 0.87 | ADORA2A (0.47) | ADORA2AADORA1ADORA2BKLKB1KLK1 | |
| SCHEMBL21722440 | 0.86 | ADORA2A (0.66) | ADORA2AADORA1ADORA2B | |
| SCHEMBL29201299 | 0.80 | ADORA2A (0.72) | ADORA2AADORA1 | |
| SCHEMBL30175507 | 0.80 | ADORA2A (0.66) | ADORA2AADORA1ADORA2B | |
| SCHEMBL21730282 | 0.80 | ADORA2A (0.66) | ADORA2AADORA1ADORA2B | |
| SCHEMBL22551977 | 0.78 | ADORA2A (0.68) | ADORA2AADORA1ADORA2B | |
| SCHEMBL22551822 | 0.77 | ADORA2A (0.64) | ADORA2AADORA1ADORA2B | |
| SCHEMBL30175528 | 0.77 | ADORA2A (0.64) | ADORA2AADORA1ADORA2B | |
| SCHEMBL28459169 | 0.77 | ADORA2A (0.50) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181092-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2024-05-03 | — | — | CN | disclosed |