Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GRN | P28799 | 1/20 | 0.30 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL422085 | 0.90 | KCNH2 (0.33) | KMT2ATNKS | |
| Hydrochloric Acid SCHEMBL21110936 | 0.88 | KCNH2 (0.32) | KMT2ATNKS | |
| SCHEMBL3732955 | 0.74 | KMT2A (0.36) | LMNAKMT2AKDM4EGRNSORT1 | |
| SCHEMBL17946249 | 0.74 | KMT2A (0.31) | ALDH1A1LMNAKMT2A | |
| SCHEMBL9316350 | 0.72 | KMT2A (0.34) | KMT2AKDM4E | |
| SCHEMBL24132990 | 0.71 | KCNH2 (0.33) | — | |
| SCHEMBL7426195 | 0.70 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL15314833 | 0.69 | KMT2A (0.36) | ALDH1A1LMNAKMT2AKDM4E | |
| SCHEMBL16904743 | 0.69 | ALDH1A1 (0.33) | ALDH1A1LMNAKDM4E | |
| SCHEMBL18472183 | 0.69 | KCNH2 (0.33) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813334-A | Onium salt, blocking agent dissociation catalyst for blocking isocyanate, blocked isocyanate composition containing blocking agent dissociation catalyst, thermosetting resin composition, cured product, and method for producing same | 广荣化学株式会社 | 2024-04-02 | — | — | CN | disclosed |