SCHEMBL29201525

SCHEMBL29201525

N#CSc1ccc2ncc(=O)[nH]c2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.46
GABRG2 P18507 2/20 0.46
GABRB3 P28472 2/20 0.46
GABRA5 P31644 2/20 0.46
GABRA2 P47869 1/20 0.46
MAPKAPK2 P49137 1/20 0.43
RPS6KA3 P51812 1/20 0.43
CSNK2A1 P68400 1/20 0.43
PLK3 Q9H4B4 1/20 0.43
ALDH1A1 P00352 7/20 0.42
GABRA3 P34903 1/20 0.41
SMYD3 Q9H7B4 3/20 0.39
CA2 P00918 1/20 0.36
CA5A P35218 1/20 0.36
MAPT P10636 5/20 0.36
POLB P06746 2/20 0.36
PIN1 Q13526 1/20 0.33
CYP1A2 P05177 3/20 0.32
HSD17B10 Q99714 2/20 0.32
CYP2C19 P33261 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL621778 0.78 PIN1 (0.53) MAPKAPK2RPS6KA3CSNK2A1PLK3ALDH1A1
Methane SCHEMBL28601514 0.76 PIN1 (0.51) MAPKAPK2RPS6KA3CSNK2A1PLK3ALDH1A1
SCHEMBL26639251 0.74 PRKCI (0.49) GABRA1GABRG2GABRB3GABRA5GABRA2
SCHEMBL30637065 0.70 MAPKAPK2 (0.50) MAPKAPK2RPS6KA3CSNK2A1PLK3ALDH1A1
SCHEMBL12178204 0.70 MAPKAPK2 (0.74) MAPKAPK2RPS6KA3CSNK2A1PLK3ALDH1A1
SCHEMBL706055 0.70 MAPKAPK2 (0.50) MAPKAPK2RPS6KA3CSNK2A1PLK3ALDH1A1
SCHEMBL29591452 0.70 RPS6KA3 (0.50) MAPKAPK2RPS6KA3CSNK2A1PLK3ALDH1A1
SCHEMBL2619124 0.70 MAPKAPK2 (0.50) MAPKAPK2RPS6KA3CSNK2A1PLK3ALDH1A1
SCHEMBL9228663 0.70 MAPKAPK2 (0.50) MAPKAPK2RPS6KA3CSNK2A1PLK3ALDH1A1
SCHEMBL622295 0.70 RPS6KA3 (0.50) MAPKAPK2RPS6KA3CSNK2A1PLK3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924194-A 7-Thiocyanoquinoxalinone compound and synthesis method thereof 延安大学 2024-04-26 CN claimed
CN-117924194-A 7-Thiocyanoquinoxalinone compound and synthesis method thereof 延安大学 2024-04-26 CN disclosed
CN-117924194-A 7-Thiocyanoquinoxalinone compound and synthesis method thereof 延安大学 2024-04-26 CN disclosed