⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19194993 | 0.81 | — | — | |
| SCHEMBL14882600 | 0.81 | NEU2 (0.32) | — | |
| SCHEMBL29012790 | 0.81 | NEU2 (0.32) | — | |
| SCHEMBL15879687 | 0.79 | LMNA (0.33) | — | |
| SCHEMBL28366315 | 0.79 | LMNA (0.33) | — | |
| SCHEMBL17404826 | 0.79 | NEU2 (0.31) | — | |
| SCHEMBL17404785 | 0.79 | NEU2 (0.31) | — | |
| SCHEMBL15640195 | 0.77 | — | — | |
| SCHEMBL16790668 | 0.77 | — | — | |
| SCHEMBL14293382 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756881-A | Targeting complement factor D degradation agent and preparation method and application thereof | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |