Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.79 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.79 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.74 |
| ▸ | BCHE | P06276 | 1/20 | 0.71 |
| ▸ | DRD2 | P14416 | 1/20 | 0.71 |
| ▸ | DRD1 | P21728 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29787915 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10ALOX15LMNA | |
| SCHEMBL1389166 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10ALOX15LMNA | |
| Methyl Coclaurine SCHEMBL29373409 | 0.93 | KDM4E (0.86) | KDM4EALDH1A1HSD17B10ALOX15LMNA | |
| SCHEMBL12807694 | 0.93 | KDM4E (0.86) | KDM4EALDH1A1HSD17B10ALOX15LMNA | |
| Methyl Coclaurine SCHEMBL12807819 | 0.93 | KDM4E (0.86) | KDM4EALDH1A1HSD17B10ALOX15LMNA | |
| Methyl Coclaurine SCHEMBL18179206 | 0.93 | KDM4E (0.86) | KDM4EALDH1A1HSD17B10ALOX15LMNA | |
| Methyl Coclaurine SCHEMBL1627504 | 0.93 | KDM4E (0.86) | KDM4EALDH1A1HSD17B10ALOX15LMNA | |
| Methyl Coclaurine SCHEMBL29365454 | 0.93 | KDM4E (0.86) | KDM4EALDH1A1HSD17B10ALOX15LMNA | |
| SCHEMBL18468569 | 0.91 | KDM4E (0.83) | KDM4EALDH1A1HSD17B10ALOX15LMNA | |
| SCHEMBL29846272 | 0.91 | KDM4E (0.83) | KDM4EALDH1A1HSD17B10ALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114891840-B | Lotus leaf O-methyltransferase and application of encoding gene thereof in synthesis of benzyl isoquinoline alkaloid and phenylpropionic acid compounds | 中国中医科学院中药研究所 | 2024-04-30 | — | — | CN | disclosed |