Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.86 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.86 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.86 |
| ▸ | DRD2 | P14416 | 1/20 | 0.83 |
| ▸ | DRD1 | P21728 | 1/20 | 0.83 |
| ▸ | BCHE | P06276 | 1/20 | 0.74 |
| ▸ | ACHE | P22303 | 1/20 | 0.74 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Coclaurine SCHEMBL29373409 | 1.00 | KDM4E (0.86) | KDM4EALDH1A1HSD17B10ALOX15DRD2 | |
| Methyl Coclaurine SCHEMBL12807819 | 1.00 | KDM4E (0.86) | KDM4EALDH1A1HSD17B10ALOX15DRD2 | |
| Methyl Coclaurine SCHEMBL18179206 | 1.00 | KDM4E (0.86) | KDM4EALDH1A1HSD17B10ALOX15DRD2 | |
| Methyl Coclaurine SCHEMBL29365454 | 1.00 | KDM4E (0.86) | KDM4EALDH1A1HSD17B10ALOX15DRD2 | |
| SCHEMBL12807694 | 0.95 | KDM4E (0.86) | KDM4EALDH1A1HSD17B10ALOX15DRD2 | |
| SCHEMBL29202140 | 0.93 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10ALOX15DRD2 | |
| SCHEMBL29787915 | 0.93 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10ALOX15DRD2 | |
| SCHEMBL1389166 | 0.93 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10ALOX15DRD2 | |
| SCHEMBL29373104 | 0.92 | DRD2 (0.89) | KDM4EALDH1A1HSD17B10ALOX15DRD2 | |
| SCHEMBL30803078 | 0.91 | BCHE (0.85) | KDM4EALDH1A1HSD17B10ALOX15DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240240194-A1 | TRANSCRIPTION FACTOR | SUN PHARMACEUTICAL INDUSTRIES AUSTRALIA PTY LIMITED (AU) | 2024-07-18 | — | — | US | claimed |
| EP-4347846-A1 | TRANSCRIPTION FACTOR | Sun Pharmaceutical Industries Australia PTY Limited (AU) | 2024-04-10 | — | — | EP | claimed |
| WO-2022249068-A1 | TRANSCRIPTION FACTOR | SUN PHARMACEUTICAL INDUSTRIES AUSTRALIA PTY LIMITED (AU) | 2022-12-01 | — | — | WO | claimed |
| US-11427827-B2 | Engineered benzylisoquinoline alkaloid epimerases and methods of producing benzylisoquinoline alkaloids | ANTHEIA, INC. (US) | 2022-08-30 | — | — | US | claimed |
| US-20190194269-A1 | POLYNUCLEOTIDES AND POLYPEPTIDES USEFUL FOR MAKING ALKALOID COMPOUNDS | INTREXON CORPORATION (US) | 2019-06-27 | — | — | US | claimed |
| US-20260103736-A1 | Methods Of Improving Production Of Morphinan Alkaloids And Derivatives | ANTHEIA INC (US) | 2026-04-16 | — | — | US | disclosed |
| US-12497638-B2 | Methods of producing epimerases and benzylisoquinoline alkaloids | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2025-12-16 | — | — | US | disclosed |
| EP-4594342-A2 | METHODS OF IMPROVING PRODUCTION OF MORPHINAN ALKALOIDS AND DERIVATIVES | Antheia, Inc. (US) | 2025-08-06 | — | — | EP | disclosed |
| US-20250137021-A1 | METHODS OF PRODUCING NOR-OPIOID AND NAL-OPIOID BENZYLISOQUINOLINE ALKALOIDS | HERCULES CAPITAL, INC., AS AGENT | 2025-05-01 | — | — | US | disclosed |
| US-12180525-B2 | Methods of producing nor-opioid and nal-opioid benzylisoquinoline alkaloids | ANTHEIA, INC. (US) | 2024-12-31 | — | — | US | disclosed |
| US-12173035-B2 | Polynucleotides and polypeptides useful for making alkaloid compounds | ANTHEIA, INC. (US) | 2024-12-24 | — | — | US | disclosed |
| US-20240240194-A1 | TRANSCRIPTION FACTOR | SUN PHARMACEUTICAL INDUSTRIES AUSTRALIA PTY LIMITED (AU) | 2024-07-18 | — | — | US | disclosed |
| EP-1632565-A1 | Modulation of alkaloid biosynthesis in plants and plants having altered alkaloid biosynthesis | JOHNSON & JOHNSON RESEARCH PTY LIMITED (AU) | 2006-03-08 | — | — | EP | disclosed |
| EP-1053303-A4 | CYTOCHROME P450 REDUCTASES FROM POPPY PLANTS | JOHNSON & JOHNSON RES PTY LTD (AU) | 2005-10-19 | — | — | EP | disclosed |
| EP-1402037-A1 | PLANT GENES INVOLVED IN DEFENSE AGAINST PATHOGENS | Syngenta Participations AG (CH) | 2004-03-31 | — | — | EP | disclosed |
| EP-1368484-A2 | PLANT GENES, THE EXPRESSION OF WHICH ARE ALTERED BY PATHOGEN INFECTION | Syngenta Participations AG (CH) | 2003-12-10 | — | — | EP | disclosed |
| WO-2003000898-A1 | PLANT GENES INVOLVED IN DEFENSE AGAINST PATHOGENS | SYNGENTA PARTICIPATIONS AG (CH) | 2003-01-03 | — | — | WO | disclosed |
| WO-2002022675-A2 | PLANT GENES, THE EXPRESSION OF WHICH ARE ALTERED BY PATHOGEN INFECTION | SYNGENTA PARTICIPATIONS AG (CH) | 2002-03-21 | — | — | WO | disclosed |
| EP-1053303-A1 | CYTOCHROME P450 REDUCTASES FROM POPPY PLANTS | JOHNSON & JOHNSON RESEARCH PTY LIMITED (AU) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999011765-A1 | CYTOCHROME P450 REDUCTASES FROM POPPY PLANTS | JOHNSON & JOHNSON RESEARCH PTY. LIMITED (AU) | 1999-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12173035-B2 | Polynucleotides and polypeptides useful for making alkaloid compounds | TARBP1, RNMT, RRP1B | KDM4E 4388/4885ALDH1A1 4597/4885HSD17B10 4423/4885 |
| US-20260103736-A1 | Methods Of Improving Production Of Morphinan Alkaloids And Derivatives | OPRK1, OPRM1, OPRD1 | KDM4E 3363/4885ALDH1A1 476/4885HSD17B10 60/4885 |
| US-20190194269-A1 | POLYNUCLEOTIDES AND POLYPEPTIDES USEFUL FOR MAKING ALKALOID COMPOUNDS | TARBP1, RNMT, RRP1B | KDM4E 4388/4885ALDH1A1 4597/4885HSD17B10 4423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.