Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29204624 | 0.92 | KMT2A (0.36) | HPGDHSD17B10MEN1KMT2AS1PR1 | |
| SCHEMBL19066431 | 0.86 | LCLAT1 (0.35) | KMT2AADORA2AS1PR1S1PR3S1PR5 | |
| SCHEMBL29204603 | 0.85 | HDAC1 (0.36) | ADORA2APDE4DIRAK4 | |
| SCHEMBL19066440 | 0.84 | LCLAT1 (0.37) | SMN1; SMN2KMT2AROCK2TSHRLCLAT1 | |
| SCHEMBL31239126 | 0.84 | LCLAT1 (0.37) | SMN1; SMN2KMT2AROCK2TSHRLCLAT1 | |
| SCHEMBL24297127 | 0.84 | HPGD (0.42) | MAPTNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL30484550 | 0.84 | ADORA2A (0.38) | NPC1RAB9ASMN1; SMN2HPGDKMT2A | |
| SCHEMBL29204572 | 0.84 | CYP1A2 (0.38) | MAPTCYP1A2ALDH1A1 | |
| SCHEMBL24297149 | 0.84 | KMT2A (0.35) | NPC1RAB9AHPGDHSD17B10MEN1 | |
| SCHEMBL29204612 | 0.84 | HDAC1 (0.38) | HPGDHSD17B10MEN1KMT2AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354931-A | Substituted oxazole derivative and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-30 | — | — | CN | disclosed |