Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30055616 | 1.00 | HSP90AA1 (0.39) | HSP90AA1MEN1KMT2AAKR1C3PRMT5 | |
| SCHEMBL27166148 | 0.89 | HSP90AA1 (0.39) | HSP90AA1MEN1KMT2AAKR1C3PRMT5 | |
| SCHEMBL27166122 | 0.88 | HSP90AA1 (0.41) | HSP90AA1AKR1C3PRMT5WDR77SLC6A2 | |
| SCHEMBL29205181 | 0.86 | PROKR1 (0.42) | HSP90AA1AKR1C3PRMT5WDR77POLB | |
| SCHEMBL27166144 | 0.83 | HSP90AA1 (0.41) | HSP90AA1PRMT5WDR77SLC6A4PROKR1 | |
| SCHEMBL29205179 | 0.82 | HSP90AA1 (0.37) | HSP90AA1AKR1C3PRMT5WDR77SLC6A2 | |
| SCHEMBL27166096 | 0.81 | PROKR1 (0.47) | HSP90AA1PRMT5WDR77HSD11B1PROKR1 | |
| SCHEMBL27166125 | 0.80 | NAMPT (0.44) | MEN1KMT2AHSD11B1PROKR1 | |
| SCHEMBL30055652 | 0.80 | NAMPT (0.44) | MEN1KMT2AHSD11B1PROKR1 | |
| SCHEMBL30055886 | 0.79 | NAMPT (0.45) | MEN1KMT2AHSD11B1PROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794899-A | Novel heterocyclic compounds, compositions, methods of preparation and uses thereof | 欧加农研发芬兰有限公司 | 2024-03-29 | — | — | CN | disclosed |