Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 4/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27166148 | 0.89 | HSP90AA1 (0.39) | PROKR1AKR1C3HSP90AA1PRMT5WDR77 | |
| SCHEMBL29205179 | 0.89 | HSP90AA1 (0.37) | PROKR1AKR1C3HSP90AA1PRMT5WDR77 | |
| SCHEMBL29205149 | 0.86 | HSP90AA1 (0.39) | PROKR1AKR1C3HSP90AA1PRMT5WDR77 | |
| SCHEMBL30055616 | 0.86 | HSP90AA1 (0.39) | PROKR1AKR1C3HSP90AA1PRMT5WDR77 | |
| SCHEMBL30055918 | 0.85 | HSP90AA1 (0.36) | PROKR1AKR1C3HSP90AA1PRMT5WDR77 | |
| SCHEMBL27166098 | 0.85 | HSP90AA1 (0.36) | PROKR1AKR1C3HSP90AA1PRMT5WDR77 | |
| SCHEMBL27166122 | 0.84 | HSP90AA1 (0.41) | AKR1C3HSP90AA1PRMT5WDR77SLC6A4 | |
| SCHEMBL27166096 | 0.84 | PROKR1 (0.47) | PROKR1HSP90AA1PRMT5WDR77NPC1 | |
| SCHEMBL27166198 | 0.83 | HSP90AA1 (0.38) | AKR1C3HSP90AA1PRMT5WDR77POLB | |
| SCHEMBL27166104 | 0.80 | ALDH1A1 (0.50) | PROKR1AKR1C3POLBNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334289-B1 | NOVEL HETEROCYCLIC COMPOUNDS, COMPOSITIONS, METHODS OF PREPARATION AND USES THEREOF | Organon R&D Finland Oy (FI) | 2025-06-25 | — | — | EP | disclosed |
| CN-117794899-A | Novel heterocyclic compounds, compositions, methods of preparation and uses thereof | 欧加农研发芬兰有限公司 | 2024-03-29 | — | — | CN | disclosed |