Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | USP10 | Q14694 | 1/20 | 0.45 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.45 |
| ▸ | USP13 | Q92995 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5568259 | 0.79 | EGFR (0.65) | EGFRMEN1KMT2AABCG2 | |
| SCHEMBL29205283 | 0.79 | KDM4E (0.54) | EGFRMEN1KMT2AHTT | |
| SCHEMBL5569052 | 0.77 | EGFR (0.70) | EGFRABCG2KDRHTT | |
| SCHEMBL4365946 | 0.77 | MAP4K4 (0.65) | EGFRMEN1KMT2AUSP10PIK3C3 | |
| SCHEMBL2776717 | 0.77 | IRAK4 (0.57) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11087812 | 0.76 | EGFR (0.68) | EGFRABCG2KDRHTT | |
| SCHEMBL29728044 | 0.76 | MAP4K4 (0.59) | EGFRFERMT2 | |
| SCHEMBL2774951 | 0.76 | MAP4K4 (0.59) | EGFRFERMT2 | |
| SCHEMBL5568844 | 0.74 | KDR (0.64) | EGFRABCG2FGFR1FLT1KDR | |
| SCHEMBL28938266 | 0.73 | MEN1 (0.48) | EGFRMEN1KMT2AABCG2FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999075-A | Compounds and pharmaceutical compositions comprising inhibitors of amyloid peptide interaction with glycosaminoglycans, methods of treatment, and uses thereof | 吉斯莫治疗股份有限公司 | 2024-05-07 | — | — | CN | disclosed |