Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.73 |
| ▸ | RECQL | P46063 | 2/20 | 0.73 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29205676 | 1.00 | KDM4E (0.73) | KDM4ERECQLNPC1RAB9AMEN1 | |
| SCHEMBL13675886 | 0.85 | TRPV1 (0.66) | KDM4ERECQLNPC1RAB9AMEN1 | |
| SCHEMBL15740334 | 0.85 | KDM4E (1.00) | KDM4ERECQLNPC1RAB9AMEN1 | |
| SCHEMBL12172761 | 0.85 | KDM4E (1.00) | KDM4ERECQLNPC1RAB9AMEN1 | |
| SCHEMBL16283211 | 0.84 | KMT2A (0.78) | KDM4ERECQLNPC1RAB9AMEN1 | |
| SCHEMBL12190069 | 0.82 | KDM4E (0.74) | KDM4ERECQLNPC1RAB9AMEN1 | |
| SCHEMBL14782069 | 0.81 | MEN1 (0.84) | KDM4ERECQLNPC1RAB9AMEN1 | |
| SCHEMBL19631338 | 0.81 | HDAC6 (0.73) | KDM4ERECQLNPC1RAB9AMEN1 | |
| SCHEMBL21356262 | 0.81 | HDAC6 (0.73) | KDM4ERECQLNPC1RAB9AMEN1 | |
| Salubrinal SCHEMBL6477833 | 0.81 | MEN1 (1.00) | KDM4ERECQLNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117945998-A | Ortho-selective deuteration method for aromatic amide compounds | 浙大宁波理工学院 | 2024-04-30 | — | — | CN | disclosed |